Cryoglobulinemic glomerulonephritis with underlying occult HBV infection and Waldenström macroglobulinemia

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Waldenström macroglobulinemia: a role of HCV infection?

Waldenstrom’s macroglobulinemia is a rare B,lymphocyte neoplasia characterized by monoclonal production of IgM Igs and by a marrow containing a diffuse infiltrate of plasmocytoid lymphocytes. The etiology of the disease is at present unknown, though epidemiological surveys suggested a possible role of the chronic antigenic stimulation.’ Because it is known that HCV infection is closely related ...

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Waldenström macroglobulinemia.

Waldenström macroglobulinemia is a lymphoplasmacytic lymphoma. A serum monoclonal IgM protein is required to establish this diagnosis. The clinical features patients develop include normochromic normocytic anemia, thrombocytopenia, hepatosplenomegaly, lymphadenopathy and signs of hyperviscosity. The International Staging System for Waldenström macroglobulinemia divides patients prognostically ...

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Extramedullary Waldenström macroglobulinemia.

Disease assessment in Waldenstrom Macroglobulinemia (WM) is dependent on the percent involvement of B-cell neoplasm in the bone marrow and IgM paraprotein in the serum. A subset of patients also demonstrates extramedullary involvement, which is infrequently examined. The role of extramedullary involvement in the diagnosis and prognosis of WM is poorly understood. The purpose of this study is to...

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CNS Vasculitis Associated with Waldenström Macroglobulinemia

Waldenström macroglobulinemia (WM) is an indolent B cell lymphoproliferative disorder with monoclonal IgM secretion. We present a patient with WM who presented with multifocal acute cortical ischemic strokes and was found to have central nervous system (CNS) vasculitis. Workup was negative for cryoglobulins and hyperviscosity syndrome. Immunosuppression with intravenous steroids and cyclophosph...

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Clinicopathological features of cryoglobulinemic glomerulonephritis associated with HBV infection: a retrospective analysis of 8 cases in China.

AIMS We retrospectively analyzed clinicopathologic features of 8 cases of hepatitis B virus-associated glomerulonephritis with hyaline thrombi, to confirm the diagnosis of cryoglobulinemic glomerulonephritis (CRYGN) associated with HBV infection. METHODS Retrospective analysis was carried out with demographic information, clinical manifestations, laboratory parameters, pathological and progno...

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ژورنال

عنوان ژورنال: Medicine

سال: 2021

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000024792